Importance

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Abstract

A chemical modification method of a defined area on a substrate surface, comprising the steps of:

a) providing a flow cell having a reactive substrate surface,b) providing a laminar flow of a first fluid comprising a first reagent and a laminar flow of a second fluid comprising a second reagent, adjacent to the flow of the first fluid, such that the two laminar fluids flow together over the reactive substrate surface with an interface to each other and,c) dynamically controlling the relative flow rates of the first and second fluids to position the interface so that a predetermined area of the reactive substrate surface is repeatedly exposed to both the first and the second fluid to obtain a chemically modified predetermined area of the substrate surface.

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First Claim