ANALYSIS OF THE METHYLATION PATTERN OF THE ALPHA-SYNUCLEIN GENE FROM DNA OF PERIPHERAL BLOOD MONOCYTES FOR DIAGNOSING PARKINSON'S DISEASE
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United States of America Patent
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Issued Date -
Nov 21, 2013
app pub date -
Jan 26, 2012
filing date -
Jan 26, 2011
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Abstract
A method of using peripheral blood monocytes of a patient to at least one of diagnose and assess a risk of a patient of developing Parkinson's disease includes obtaining peripheral blood monocytes from the patient, and determining a methylation pattern of the SNCA(−926/−483) region of the SNCA gene of the DNA of the peripheral blood monocytes.
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