TREATMENT OF AMYLOID BETA AMYLOIDOSIS
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United States of America Patent
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Issued Date -
Nov 21, 2013
app pub date -
Mar 14, 2013
filing date -
May 18, 2012
priority date (Note) -
Abandoned
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Abstract
Provided is a method for the treatment and/or prevention of an amyloid beta amyloidosis in a subject comprising the step of administering to the subject an effective amount of a 5-lipoxygenase-activating protein (FLAP) antagonist. In preferred embodiments, the FLAP antagonist is MK-591, or a pharmaceutically acceptable salt thereof. Also provided is a method for decreasing or preventing the deposition of beta amyloid in the brain of a subject comprising the step of administering to a subject an effective amount of a FLAP antagonist. In preferred embodiments, the FLAP antagonist is MK-591, or a pharmaceutically acceptable salt thereof.
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