COVALENTLY LINKED INTERLEUKIN-10

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United States of America Patent

APP PUB NO 20130316404A1
SERIAL NO

13989425

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a polypeptide having interleukin-10 function, comprising two interleukin-10 monomer subunits covalently linked by a linker. The present invention further relates to a nucleic acid molecule encoding the polypeptide of the invention, a vector comprising said nucleic acid molecule, a non-human host transformed with the nucleic acid molecule or the vector of the invention as well as a method for the production of a recombinant polypeptide of the invention. The present invention further relates to a pharmaceutical composition as well as to the polypeptide, the nucleic acid molecule, the vector or the host or host cell of the invention for use in treating and/or preventing inflammatory diseases.

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Patent Owner(s)

Patent OwnerAddress
THE UNIVERSITY OF MANCHESTERMANCHESTER M13 9PL

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lanvermann, Sebastian Dresden, DE 1 7
Müller, Werner Köln, DE 22 127
Roers, Axel Dresden, DE 1 7

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