METHOD FOR IMMOBILIZING TEMPERATURE RESPONSIVE PROTEIN A
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United States of America Patent
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Issued Date -
Nov 28, 2013
app pub date -
Dec 26, 2011
filing date -
Dec 24, 2010
priority date (Note) -
Abandoned
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Abstract
A method for manufacturing a carrier having temperature responsive protein A, which is protein A mutated such that a binding property to an antibody changes depending upon temperature, immobilized thereto, wherein the temperature responsive protein A has the binding property to the antibody in a first temperature region and no binding property to the antibody in a second temperature region; and the method comprises a step of immobilizing the temperature responsive protein A to a carrier surface at a temperature within the first temperature region in which the temperature responsive protein A has the binding property to the antibody.
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