Chemiluminescence-based haemostasis assay

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United States of America Patent

PATENT NO 9856510
SERIAL NO

13993992

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Abstract

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The present invention relates to a method for in vitro determining generation of a haemostatis factor such as thrombin and/or plasmin in a test sample using a chemiluminescent substrate specific for said blood clotting factor. Upon cleavage of the substrate, a luminescent signal is generated via aminoluceferin with the aid of a luciferase. The invention also relates to a kit for in vitro determining generation of a haemostasis factor in a test sample, and to novel chemiluminescent substrates for the determination of thrombin and plasmin.

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Patent Owner(s)

Patent OwnerAddress
STICHTING KATHOLIEKE UNIVERSITEITGEERT GROOTEPLEIN 9 NIJMEGEN 6525
CHIRALIX B VTOERNOOIVELD 100 NIJMEGEN NL-6525 EC

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Blaauw, Richard Hendrik The Netherlands, NL 5 6
van, Heerde Waander Laurens Nijmegen, NL 4 1

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