Methods and compositions related to internalizing RGD peptides

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United States of America Patent

PATENT NO 9115170
APP PUB NO 20130343989A1
SERIAL NO

13754105

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Abstract

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Disclosed are compositions and methods useful for targeting tissue undergoing angiogenesis or to cells or tissue expressing αv integrins. The compositions and methods are based on peptide sequences that selectively bind to and home to tissue undergoing angiogenesis or to cells or tissue expressing αv integrins in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tissue experiencing angiogenesis or to cells or tissue expressing αv integrins.

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Patent Owner(s)

  • SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ruoslahti, Erkki Buellton, US 115 2304
Sugahara, Kazuki Goleta, US 13 148
Teesalu, Tambet Goleta, US 15 127

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