METHOD TO DETECT PROSTATE CANCER IN A SAMPLE

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20130344487A1
SERIAL NO

14011988

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides methods to detect prostate cancer by detecting the RNA encoded by PCA3. The disclosure provides a method for determining a predisposition, or presence of prostate cancer comprising: (a) contacting a sample with at least one oligonucleotide that hybridizes to a PCA3 polynucleotide; (b) detecting an amount of PCA3 and second prostate-specific polynucleotides; and (c) comparing the amount of PCA3 polynucleotide that hybridizes to the oligonucleotide to a predetermined cut off value, and determining the presence or absence of prostate cancer. Diagnostic kits are provided for detecting prostate cancer or the risk of developing same comprising: (a) at least one container means containing at least one oligonucleotide probe or primer that hybridizes to PCA3 (b) at least one oligonucleotide probe or primer that hybridizes with a second prostate specific nucleic acid; and (c) reagents for detecting PCA3 and the second prostate specific nucleic acid.

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Patent Owner(s)

Patent OwnerAddress
GEN-PROBE INCORPORATED10210 GENETIC CENTER DRIVE ATTN PATENT DEPT SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chypre, Camille Annecy, FR 14 77
Fradet, Yves Quebec, CA 20 112
Garon, Genevieve Saint-Augustin-de-Desmaures, CA 6 37
Piche, Lyson Cap-Sante, CA 5 25

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