Multipole ion guide interface for reduced background noise in mass spectrometry

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United States of America Patent

PATENT NO 8723107
APP PUB NO 20140008530A1
SERIAL NO

13932716

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Ions that are transported from an ion source to a mass spectrometer for mass analysis are often accompanied by background particles such as photons, neutral species, and cluster or aerosol ions which originate in the ion source. Background particles are also produced by scattering and neutralization of ions during collisions with background gas molecules in higher pressure regions with line-of-sight to the mass spectrometer detector. In either case, such background particles produce noise in mass spectra. Apparatus and methods are provided in which a multipole ion guide is configured to efficiently transport ions through multiple vacuum stages, while preventing background particles, produced both in the ion source and along the ion transport pathway, from reaching the detector, thereby improving signal-to-noise in mass spectra.

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Patent Owner(s)

  • PERKINELMER HEALTH SCIENCES, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Welkie, David G Trumbull, US 36 806
Whitehouse, Craig M Branford, US 82 3092

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