SELF-ASSEMBLING NANOPARTICLE DRUG DELIVERY SYSTEM
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United States of America Patent
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Issued Date -
Jan 9, 2014
app pub date -
Jan 18, 2012
filing date -
Apr 9, 2007
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Abandoned
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Abstract
A self-assembling nanoparticle drug delivery system for the delivery of various bioactive agents including peptides, proteins, nucleic acids or synthetic chemical drugs is provided. The self-assembling nanoparticle drug delivery system described herein includes viral capsid proteins, such as Hepatitis B Virus core protein, encapsulating the bioactive agent, a lipid layer or lipid/cholesterol layer coat and targeting or facilitating molecules anchored in the lipid layer. A method for construction of the self-assembling nanoparticle drug delivery system is also provided.
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