FRMD4A ANTAGONISTS AND THEIR USES
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United States of America Patent
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Issued Date -
Jan 23, 2014
app pub date -
Feb 9, 2012
filing date -
Feb 9, 2011
priority date (Note) -
Abandoned
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Abstract
An antagonist of FERM domain-containing protein 4A (FRMD4A) and/or of the Hippo pathway for use in a method of treating a cancer in a mammalian subject, wherein the cancer is selected from: squamous cell carcinoma (SCC), an epithelial cancer, an adenocarcinoma and a carcinoma is disclosed, as well as related methods of treatment of cancer, methods of screening and generating such antagonists, including anti-FRMD4A antibodies.
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