METHOD FOR DETERMINING THE EFFICACY OF A COMBINATION THERAPY
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United States of America Patent
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app pub date -
Sep 18, 2013
filing date -
Jun 30, 2009
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Abstract
The present invention concerns the determination of weighted phenotypic sensitivity score (wPSS) for a combination therapy as being the combination of information about the inherent anti-viral potency of each drug, as determined through statistical analysis of response to anti-retroviral therapy combination regimens, with resistance information on the individual patient's virus to each anti-retroviral drug as well as the use of this wPSS for predicting the efficacy of a patient's therapy or for evaluating or optimizing a therapy.
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