BIOMARKERS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

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United States of America Patent

APP PUB NO 20140030735A1
SERIAL NO

14003120

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The methods described herein are based on the discovery that the plasma level of a panel of specific proteins differs between two subject populations: 1) subjects at risk for chronic obstructive pulmonary disease (“COPD”) but not manifesting clinical symptoms of COPD; and 2) subjects having very severe COPD. The difference in plasma levels is statistically significant for each protein. The identification of these proteins thus facilitates susceptibility detection, early disease detection, disease severity assessment, disease progression monitoring, and therapy efficacy monitoring.

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Patent Owner(s)

Patent OwnerAddress
TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONBROAD AND MONTGOMERY AVENUE PHILADELPHIA PA 19122

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barrero, Carlos A Philadelphia, US 9 15
Kelsen, Steven G Rydal, US 4 13
Merali, Salim Bryn Mawr, US 14 15

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