Suppressor tRNA Transcription in Vertebrate Cells

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United States of America Patent

APP PUB NO 20140045259A1
SERIAL NO

13851911

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in vertebrate cells. The components include orthogonal tRNA's, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNA's/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in vertebrate cells are also provided.

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Patent Owner(s)

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AMBRX INC10975 NORTH TORREY PINES ROAD LA JOLLA CA 92037

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHU, Stephanie Simi Valley, US 17 639
NORMAN, Thea Clinton, US 56 1913
TIAN, Feng San Diego, US 160 3003

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