Sample component trapping, release, and separation with membrane assemblies interfaced to electrospray mass spectrometry
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United States of America Patent
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Apr 5, 2016
Grant Date -
Feb 20, 2014
app pub date -
Jul 15, 2013
filing date -
May 19, 2005
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Abstract
A method and apparatus to trap, release and/or separate sample components in solution passing through a channel with or without packing material present by passing ion current through the channel driven by an electric field. A portion of the ion current includes cation and/or anion species generated from second solution flows separated from the sample solution flow path by semipermeable membranes. Cation and/or anion species generated in the second solution flow regions are transferred into the sample solution flow path through ion selective semipermeable membranes. Ion current moving along the sample solution flow path is controlled by varying the composition of the second solutions and/or changing the voltage between membrane sections for a given sample solution composition. The sample composition may also be varied separately or in parallel to enhance trapping, release and/or separation efficiency and range.
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- 15 United States
- 10 France
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- 5 Korea
- 2 Other
Patent Owner(s)
- PERKINELMER HEALTH SCIENCES, INC.
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- [Patents Count]
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
White, Thomas P | Clinton, US | 10 | 88 |
Whitehouse, Craig M | Branford, US | 82 | 3093 |
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11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Oct 5, 2027 |
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