TREATMENT OF MULTIPLE MYELOMA WITH MASITINIB
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United States of America Patent
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Issued Date -
Feb 20, 2014
app pub date -
Apr 4, 2012
filing date -
Apr 8, 2011
priority date (Note) -
Abandoned
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Abstract
The present invention relates to the treatment of multiple myeloma, especially for the treatment of those patients with refractory or first relapsed multiple myeloma, and in particular patients with t(4;14) multiple myeloma, comprising administration of a tyrosine kinase inhibitor or a mast cell inhibitor, especially masitinib or a pharmaceutically acceptable salt thereof, administered in association with an additional care in multiple myeloma; for example, autologous stem-cell transplantation, targeted therapies, anti-myeloma agents such as alkylating agents, corticosteroids, or immunomodulatory agents, including bortezomib, lenalidomide, and dexamethasone.
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