METHOD OF DIAGNOSING ALZHEIMERS DISEASE USING SALIVA

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United States of America Patent

APP PUB NO 20140057364A1
SERIAL NO

13801925

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Abstract

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Provided is a method of diagnosing Alzheimer's disease. The method of diagnosing Alzheimer's disease includes preparing magnetic particles having primary capture antibodies specifically bonded with beta-amyloid adsorbed thereon, introducing saliva containing beta-amyloid into the magnetic particles to bond the beta-amyloid contained in the saliva with the primary capture antibodies, bonding secondary capture antibodies labeled with fluorescent substances to the magnetic particles bonded with the beta-amyloid to form a complex, disposing the complex in a channel region of an photoelectric conversion device in which photoelectric current is changed according to an amount of incident light, and measuring photoelectric current changed by light excited from the complex to quantify a concentration of the beta-amyloid contained in the saliva.

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Patent Owner(s)

Patent OwnerAddress
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE218 GAJEONG-RO YUSEONG-GU DAEJEON 34129

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
KIM, Chang-Beom Seoul, KR 12 68
KIM, Kwan Su Seoul, KR 7 29
SONG, Kibong Daejeon, KR 39 140

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