NOVEL GENES AND PROTEINS THAT HOME TO DEVELOPING MICROVESSELS
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United States of America Patent
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Issued Date -
Mar 6, 2014
app pub date -
Apr 15, 2013
filing date -
Dec 1, 2006
priority date (Note) -
Abandoned
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Abstract
Described herein are polypeptides that home to developing microvasculature, (also referred to as developing microvessels), such as newly developing microvasculature in mammals, particularly in humans, and to DNA that encodes such polypeptides. These polypeptides are referred to herein as developing microvasculature homing polypeptides. In a specific embodiment, the homing peptides are collateral vessel endothelia (CVE) homing polypeptides, which have been shown to home to collateral vessel endothelia after ischemia.
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