Substrates for Drug Delivery Device and Methods of Preparing and Use
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United States of America Patent
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Issued Date -
Mar 13, 2014
app pub date -
Nov 13, 2013
filing date -
Aug 4, 2003
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
An assembly and method for producing a condensation aerosol are disclosed. The assembly includes a heat-conductive metal substrate with an oxidation resistant exterior surface and a drug composition film on the exterior surface and is for use in an aerosol device. The thickness of the film and the surface of the substrate is such that the aerosol formed by vaporizing and condensing the drug composition the aerosol contain 10% by weight or less drug-degradation products and at least 50% of the total amount of the drug composition in the film. The methods for treating the exterior surface include heat and chemical treatment and formation of a protective overcoat.
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