PRODRUGS OF DHODH INHIBITORS AND THEIR USES
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United States of America Patent
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Issued Date -
Mar 20, 2014
app pub date -
Sep 19, 2012
filing date -
Sep 19, 2012
priority date (Note) -
Abandoned
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Abstract
The invention generally relates to Pro-Drugs of dihydroorotate dehydrogenase (DHODH) inhibitors and methods of use thereof. In certain embodiments, the invention provides a DHODH inhibitor compound including a cleavable functional group that increases bioavailability as compared to a form of the DHODH inhibitor without the functional group, rendering the former more suitable for therapeutic use.
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