Bis-Quaternary Ammonium Cyclophane Compounds that Interact with Neuronal Nicotinic Acetylcholine Receptors

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United States of America Patent

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14087643

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Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.

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UNIVERSITY OF KENTUCKY RESEARCH FOUNDATIONLEXINGTON KY

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Inventor Name Address # of filed Patents Total Citations
Allen, Davis Rootstown, US 1 0
Crooks, Peter Nicholasville, US 35 101
Dwoskin, Linda Lexington, US 8 4
Lockman, Paul Amarillo, US 5 2
Sumithran, Sangeetha Lexington, US 13 33
Zheng, Guangrong Lexington, US 32 68
Zheng, Zhenfa Lexington, US 5 1

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