Dual affinity polypeptides for purification

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United States of America Patent

PATENT NO 9376463
SERIAL NO

14086621

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Abstract

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The present invention relates to a process for purification of a target biomolecule, comprising the steps: (a) contacting (i) a target biomolecule, (ii) a dual affinity polypeptide, and (iii) a solid support comprising a catching ligand, wherein the ratio between the equilibrium dissociation constants of the dual affinity polypeptide, [KD,t/KD,s], is at least 100 at standard conditions; and (b) recovering the target biomolecule by elution.

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Patent Owner(s)

Patent OwnerAddress
CHRETO APS3500 VÆRLØSE

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kyhse-Andersen, Jan Værløse, DK 5 4

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