Use of Epigallocatechin Gallate as an Antiviral Agent against infections by the Hepatitis C Virus

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United States of America Patent

APP PUB NO 20140088184A1
SERIAL NO

14008031

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Abstract

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The present invention relates to a flavonoid compound having the formula I, where R3, R5 and/or R7 is a group having the formula II, or R1 and R2 are both OH groups, or to one of the pharmaceutically acceptable salts or esters thereof, for use as an antiviral agent in the treatment and/or prevention of a hepatitis C virus (HCV) infection. The invention also relates to an ex vivo method for reducing the infectivity of HCV or for inactivating HCV, including a step of contacting said hepatitis C virus with a compound having the formula (I).

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Patent Owner(s)

Patent OwnerAddress
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C N R S )75016 PARIS
INSTITUT PASTEUR DE LILLE59019 LILLE CEDEX

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dubuisson, Jean Faches-Thumesnil, FR 8 4
Rouille, Yves Wasquehal, FR 2 4
Seron, Karin Saint-Omer, FR 3 4
Wychowski, Czeslaw Meurchin, FR 6 32

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