KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy

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United States of America Patent

PATENT NO 9629934
APP PUB NO 20140107041A1
SERIAL NO

14019241

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Abstract

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The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a KD<1 μM), and dimer and multimeric constructs comprising these polypeptides.

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Patent Owner(s)

  • DYAX CORP.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dransfield, Daniel T Hason, US 42 433
Ladner, Robert Charles Ijamsville, US 82 1582
Sato, Aaron K Richmond, US 45 722
Sexton, Daniel J Melrose, US 58 508

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