COMPOSITIONS AND METHODS FOR TREATMENT AND DELAYING THE ONSET OF DIABETES
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United States of America Patent
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Issued Date -
Apr 17, 2014
app pub date -
Oct 14, 2013
filing date -
Jul 21, 2004
priority date (Note) -
Abandoned
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Abstract
Disclosed herein are methods of delaying the onset or treating diabetes that comprises administering a uric acid lowering agent. The inventors have made the remarkable discovery that elevated uric acid levels are not a corollary to insulin resistance, but rather a primary mediator of insulin resistance. Specifically exemplified are methods that involve administering to a patient susceptible to development of diabetes a composition comprising a uric acid lowering agent in a regimen that maintains serum uric acid levels below at least 5.2 to 5.5 mg/dl.
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