Methods and compositions for reducing Shiga toxin induced toxicity in mammals

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United States of America Patent

PATENT NO 9439438
SERIAL NO

14111444

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Abstract

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Manganese compositions effective in reducing Shiga toxin-induced toxicity in mammals infected with Shiga toxin-producing bacteria such as E. coli O157:H7 are described. Manganese compositions described herein can be combined with antibiotic therapy as manganese can block the toxic effects of Shiga toxin released from dying bacteria.

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Patent Owner(s)

  • CARNEGIE MELLON UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Linstedt, Adam D Pittsburgh, US 3 2
Mukhopadhyay, Somshuvra Austin, US 4 2

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