DNA-binding proteins and uses thereof

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United States of America Patent

PATENT NO 8912138
SERIAL NO

14065055

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Abstract

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Disclosed herein are polypeptides, polynucleotides encoding, cells and organisms comprising novel DNA-binding domains, including TALE DNA-binding domains. Also disclosed are methods of using these novel DNA-binding domains for modulation of gene expression and/or genomic editing of endogenous cellular sequences.

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Patent Owner(s)

  • SANGAMO THERAPEUTICS, INC.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gregory, Philip D Richmond, US 75 3037
Miller, Jeffrey C Richmond, US 104 3609
Paschon, David Richmond, US 62 1890
Rebar, Edward J Richmond, US 90 3874
Tan, Siyuan Richmond, US 28 1168
Urnov, Fyodor Richmond, US 106 4586
Zhang, Lei Richmond, US 2471 17753

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