CB-183,314 COMPOSITIONS AND RELATED METHODS
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United States of America Patent
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Issued Date -
May 15, 2014
app pub date -
Oct 7, 2013
filing date -
May 26, 2011
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present disclosure provides novel solid CB-183,315 formulations which have improved chemical stability. The chemical stability of the solid CB-183,315 is dependent on the process by which the composition is made. Solid preparations of CB-183,315 can be prepared by the following method: (a) forming an aqueous solution of CB-183,315 and at least one sugar that (e.g., sucrose, trehalose or dextran) at a pH of 2-7, preferably pH 6 and (b) converting the aqueous solution to the solid preparation of CB-183,315 (e.g., via lyophilization or spray drying).
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