DENSOVIRUS-DERIVED VECTOR FOR GENE TRANSFER IN INSECTS
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United States of America Patent
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Issued Date -
May 22, 2014
app pub date -
Nov 2, 2011
filing date -
Nov 2, 2010
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a vector including: (i) an inverted terminal repeat (ITR) nucleotide sequence at the 5′ position; (ii) a nucleotide sequence functionally bonded to a promoter at the central position, said nucleotide sequence coding for a toxin; and (iii) an inverted terminal repeat (ITR) nucleotide sequence at the 3′ position, wherein said vector does not include any viral nucleotide sequences of Junonia coenia densovirus other than the ITR sequences according to (i) and (iii). The present invention also relates to a method for producing recombinant and nonreplicative particles of Junonia coenia densovirus (JcDNV) using such a vector. Finally, the present invention relates to the use of recombinant and nonreplicative particles of Junonia coenia densovirus produced according to the above-described method as a moth-control agent.
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