METHOD OF A TEST STRIP DETECTING CONCENTRATION OF AN ANALYTE OF A SAMPLE, THREE-ELECTRODE TEST STRIP, AND METHOD OF UTILIZING A TEST STRIP DETECTING DIFFUSION FACTOR
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United States of America Patent
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Issued Date -
Jun 26, 2014
app pub date -
Dec 22, 2013
filing date -
Dec 23, 2012
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Abstract
A method of a test strip detecting concentration of an analyte of a sample includes placing the sample in a reaction region of the test strip, wherein the analyte reacts with an enzyme to generate a plurality of electrons, and the plurality of electrons are transferred to a working electrode of the reaction region through a mediator; applying an electrical signal to the working electrode; measuring a first current through the working electrode during a first period; the mediator generating an intermediate according to the electrical signal during a second period; measuring a second current through the working electrode during a third period; calculating initial concentration of the analyte according to the first current; calculating a diffusion factor of the intermediate in the sample according to the second current; and correcting the initial concentration to generate new concentration of the analyte according to the diffusion factor.
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