Methods of acquiring genome size and error
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United States of America Patent
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Issued Date -
Jul 3, 2014
app pub date -
May 17, 2011
filing date -
May 17, 2011
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Abstract
Provided is a method of acquiring genome size. The method comprises steps of sequencing random fragments of whole genome, acquiring all of k-mer information including k-mer depth, counting frequency of each k-mer depth value so as to determine expected k-mer depth, and acquiring the genome size by dividing the sum of k-mers by the expected k-mer depth. The method is convenient, rapid, and cost-effective. Also provided is a method of acquiring error of sequencing genome based on all of k-mer information including k-mer depth.
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