Antibodies binding to phosphorylcholine (PC) and/or PC conjugates

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United States of America Patent

PATENT NO 9796786
APP PUB NO 20140193413A1
SERIAL NO

14235970

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present disclosure relates to an antibody or antibody fragment capable of binding to phosphorylcholine and/or a phosphorylcholine conjugate, wherein the antibody or antibody fragment comprises a variable heavy chain (VH) domain and/or a variable light chain (VL) domain, and wherein (a) the VH domain comprises complementarity determining regions (CDRs) selected from the group consisting of: a CDR1 sequence having identity to the sequence of SEQ ID NO: 7; a CDR2 sequence having identity to the sequence of SEQ ID NO: 8; and a CDR3 sequence having identity to the sequence of SEQ ID NO: 9 or 10; and/or (b) the VL domain comprises CDRs selected from the group consisting of: a CDR4 sequence having identity to the sequence of SEQ ID NO: 11; a CDR5 sequence having identity to the sequence of SEQ ID NO: 12; a CDR6 sequence having identity to the sequence of SEQ ID NO: 13.

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Patent Owner(s)

  • ATHERA BIOTECHNOLOGIES AB;DYAX CORP.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Camber, Ola Bromma, SE 13 3
Nixon, Andrew E Hanover, US 9 13
Pettersson, Knut Göteborg, SE 17 7
Sexton, Dan Melrose, US 7 3

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