NOVEL FAB FRAGMENT LIBRARIES AND METHODS FOR THEIR USE
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United States of America Patent
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Nov 26, 2013
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May 18, 1999
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Abstract
The present invention provides Fab libraries and methods for using the Fab libraries to obtain antibodies against a target. The Fab library of the invention contains at least 109 different Fabs, and in some embodiments, at least 1010 different Fabs. The Fab libraries of the invention are used to isolate polyclonal or monoclonal Fabs that bind with high specificity to targets.
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