PROCESS FOR THE PREPARATION OF ISOXAZOLINE DERIVATIVES

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United States of America Patent

APP PUB NO 20140206633A1
SERIAL NO

13581137

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to processes for the preparation of compounds of formula IB wherein A1, A2, A3, A4, L, Y1, Y2, R1, R2, R3, R4 and R5 are as defined in the claims, comprising reacting a compound of formula (II) wherein Y1, Y2, L, A1, A2, R1, R2, R3, R4 and R5 are as defined for the compound of formula (I); with hydroxylamine in the presence of water, a base and a chiral phase transfer catalyst, which chiral phase transfer catalyst is a quinine derivative. The invention also relates to compounds of formula IB and enantiomerically enriched mixtures comprising compounds of formula IB.

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Patent Owner(s)

Patent OwnerAddress
SYNGENTA CROP PROTECTION LLC410 SWING ROAD GREENSBORO NC 27409

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cassayre, Jérôme Yves Stein, CH 12 16
El, Qacemi Myriem Stein, CH 83 49
Godineau, Edouard Stein, CH 7 2
Mulholland, Nicholas Phillip Bracknell, GB 9 2
Renold, Peter Stein, CH 95 80
Revol, Guillaume Stein, CH 1 1

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