TOPICAL BIOADHESIVE FORMULATIONS

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United States of America Patent

SERIAL NO

14143665

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Abstract

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The present invention relates to topical bioadhesive formulations comprising low viscosity, non-liquid crystalline, mixtures of: a) at least one neutral diacyl lipid and/or at least one tocopherol; b) at least one phospholipid; c) at least one biocompatible, oxygen containing, low viscosity organic solvent; wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament.

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Patent Owner(s)

Patent OwnerAddress
CAMURUS ABIDEON SCIENCE PARK 223 70 LUND SWEDEN

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
JOABSSON, Fredrik Lund, SE 23 511
LINDEN, Margareta Lund, SE 4 47
THURESSON, Krister Lund, SE 24 347
TIBERG, Fredrik Lund, SE 60 738

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