PHARMACEUTICAL COMPOSITION COMPRISING FACTOR VII ENCAPSULATED IN MICELLES
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United States of America Patent
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Issued Date -
Aug 7, 2014
app pub date -
Jul 31, 2012
filing date -
Aug 2, 2011
priority date (Note) -
Abandoned
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Abstract
The invention relates to a pharmaceutical composition comprising factor VII encapsulated in micelles formed from block copolymer molecules containing (i) a hydrophilic polymer segment consisting of a polyalkylene glycol and (ii) a hydrophobic polymer segment consisting of a polyamino acid, with said polyamino acid comprising exclusively amino acid residues selected from the group consisting of histidine, lysine, aspartic acid and glutamic acid residues, wherein a part of said amino acid residues is substituted with a hydrophobic group.
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