A Device for the Transdermal Delivery of Alkaline Compounds that are Susceptible to Degradation in Their Free Base Form
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United States of America Patent
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Issued Date -
Aug 7, 2014
app pub date -
Aug 21, 2012
filing date -
Aug 25, 2011
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
The present invention pertains generally to the field of transdermal drug delivery. More specifically, the invention relates to a device for the transdermal delivery of an alkaline pharmaceutically active compound that is susceptible to degradation in its free base form (e.g., rivastigmine) that comprises an adhesive matrix layer, a backing layer and a release or protective layer, wherein the adhesive matrix layer comprises said pharmaceutically active compound, triethylcitrate and hydrochloric acid. The invention also relates to methods of preparing such devices.
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