NOVEL METHODS FOR QUANTIFICATION OF MICRORNAS AND SMALL INTERFERING RNAS

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United States of America Patent

APP PUB NO 20140227689A1
SERIAL NO

13776179

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Abstract

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The invention relates to ribonucleic acids, probes and methods for detection, quantification as well as monitoring the expression of mature microRNAs and small interfering RNAs (siRNAs). The invention furthermore relates to methods for monitoring the expression of other non-coding RNAs, mRNA splice variants, as well as detecting and quantifying RNA editing, allelic variants of single transcripts, mutations, deletions, or duplications of particular exons in transcripts, e.g., alterations associated with human disease such as cancer. The invention furthermore relates to methods for detection, quantification as well as monitoring the expression of deoxy nucleic acids.

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Patent Owner(s)

Patent OwnerAddress
EXIQON A/SDANISH WEISS BECKER VEDBAEK REGION HOVEDSTADEN

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Echwald, Søren Morgenthaler Humlebaek, DK 15 118
Jacobsen, Nana Gentofte, DK 7 128
Kauppinen, Sakari Smorum, DK 54 1396
Kongsbak, Lars Holte, DK 26 405
Mouritzen, Peter Jyllinge, DK 12 143
Nørholm, Mikkel Copenhagen, DK 3 18
Nielsen, Peter Stein Birkerod, DK 4 72

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