PHARMACEUTICAL COMPOSITION CONTAINING WOGONIN AS AN ACTIVE INGREDIENT FOR PREVENTING OR TREATING ASTHMA

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United States of America Patent

APP PUB NO 20140228427A1
SERIAL NO

14122789

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Abstract

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The present invention relates to a pharmaceutical composition for the prevention or treatment of asthma comprising Wogonin as an active ingredient. The Wogonin of the present invention is excellent not only in relieving airway hypersensitivity that causes asthma in vivo, in inhibiting reactive oxygen species generation in the airway, and in inhibiting the infiltration of inflammatory cells in the bronchus, but also in inhibiting the generation of IgE in serum and bronchoalveolar lavage fluid, and in inhibiting the expressions of Th2 cytokines in the lung. Therefore, the Wogonin of the present invention can be effectively used as a composition for the prevention, treatment, or improvement of asthma.

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Patent OwnerAddress
KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY125 GWAHAK-RO YUSEONG-GU DAEJEON 34141

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ahn, Kyung Seop Daejeon, KR 40 24
Jang, Ha Young Daejeon, KR 10 135
Kim, Doo-Young Daejeon, KR 40 133
Kim, Jung Hee Daejeon, KR 35 152
Kwon, Ok-Kyoung Daejeon, KR 20 1
Lee, Hyeong Kyu Daejeon, KR 20 11
Oh, Sei Ryang Daejeon, KR 26 24
Park, Ji Won Daejeon, KR 84 251

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