Fibroblast Growth Factor Receptor-Derived Peptides Binding to NCAM
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United States of America Patent
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Dec 24, 2013
filing date -
May 27, 2009
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Abstract
The present invention relates to the use of peptides that are capable of binding to, and modulating the activity of NCAM. The peptides are peptide fragments of FGFRs. They are derived from two distinct binding sites for binding of the immunoglobulin-like module 2 of FGFR to NCAM F3 modules 1-2. The invention further relates to use of said peptides for the production of a medicament for the treatment of different pathological conditions, wherein NCAM and/or FGFRs play a prominent role.
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