ST6GAL I MEDIATED MODULATION OF HEMATOPOIESIS

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United States of America Patent

APP PUB NO 20140242058A1
SERIAL NO

14128642

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided are methods for reducing haematocytes in an individual. The method involve administering to an individual a composition that contains recombinant a2,6-sialyltransferase (ST6Gal I). The method is suitable for prophylaxis and therapy of a condition that is positively correlated with undesirable hematopoiesis. Such conditions include autoimmune diseases, transplantation rejection, blood cancers and allergic reactions and inflammations. The invention also provides a pharmaceutical preparation that contains recombinant ST6Gal I and which is suitable for administration to an individual to reduce haematocytes in the individual, and a pharmaceutically acceptable carrier.

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Patent Owner(s)

Patent OwnerAddress
HEALTH RESEARCH INCELM AND CARLTON STREETS BUFFALO NY 14263

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kenari, Mehrab Nasiri Amherst, US 2 2
Lau, Joseph Hamburg, US 7 76

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