THROMBOSPONDIN-1 POLYPEPTIDES AND METHODS OF USING SAME
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United States of America Patent
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Issued Date -
Sep 18, 2014
app pub date -
Mar 11, 2014
filing date -
Mar 14, 2013
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Abandoned
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Abstract
The invention features thrombospondin-1 (TSP-1) polypeptides (e.g., 3TSR-Fc fusion proteins), nucleic acid molecules encoding the TSP-1 polypeptides, and compositions thereof. The invention also features methods of making and using the TSP-1 polypeptides of the invention (e.g., using 3TSR-Fc fusion proteins to treat a subject having a disorder associated with pathological angiogenesis, e.g., cancer, e.g., epithelial ovarian cancer (EOC)).
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