CRYSTAL OF ANDROGEN RECEPTOR ANTAGONISTIC COMPOUND
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United States of America Patent
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Issued Date -
Sep 18, 2014
app pub date -
Oct 19, 2012
filing date -
Oct 21, 2011
priority date (Note) -
Abandoned
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Abstract
[Problem] A crystal of (2R,5S)-4-(3-chloro-4-cyanophenyl)-N-(2-cyclopropylpyrimidin-5-yl)-2,5-dimethylpiperazine-1-carboxamide with excellent activity as an androgen receptor (AR) antagonistic compound, the salts thereof, or the solvate thereof, which is suitable for industrialization as a bulk drug of pharmaceutical products; a pharmaceutical composition comprising the crystal as an active ingredient; and the pharmaceutical composition which is the AR antagonistic drug are provided.
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