FC VARIANTS THAT IMPROVE FCRN BINDING AND/OR INCREASE ANTIBODY HALF-LIFE

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Oct 2, 2014
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Mar 13, 2014
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Mar 15, 2013

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Abstract

The present invention discloses the generation of novel variants of Fc domains, including those found in antibodies, Fc fusions, and immuno-adhesions, which have an increased binding to the FcRn receptor and/or increased serum half-life.

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XENCOR INC	111 WEST LEMON AVENUE MONROVIA CA 91016

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C07K:PEPTIDES

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Inventor Name	Address	# of filed Patents	Total Citations
Lazar, Gregory Alan	Indianapolis, US	159	7599

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FC VARIANTS THAT IMPROVE FCRN BINDING AND/OR INCREASE ANTIBODY HALF-LIFE

Number of patents in Portfolio can not be more than 2000

United States of America Patent

14210363

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14210363

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