NOVEL VACCINE
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United States of America Patent
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app pub date -
Jun 18, 2014
filing date -
Feb 23, 2001
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Abandoned
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Abstract
The invention relates to the use of an influenza antigen preparation obtainable by the following process, in the manufacture of an intradermal flu vaccine:
- (i) harvesting of virus-containing material from a culture;(ii) clarification of the harvested material to remove non-virus material;(iii) concentration of the harvested virus;(iv) a further step to separate whole virus from non-virus material;(v) splitting of the whole virus using a suitable splitting agent in a density gradient centrifugation step;(vi) filtration to remove undesired materials;wherein the steps are performed in that order but not necessarily consecutively.
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