Pharmaceutical Solid Compositions Containing Ibuprofen Salts
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United States of America Patent
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Oct 9, 2014
app pub date -
Nov 14, 2012
filing date -
Nov 17, 2011
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Abstract
A pharmaceutical, non-effervescent, solid composition comprising a mixture of a pharmaceutically effective amount of a ibuprofen salt and a pharmaceutically acceptable strong base in a molar ratio of from 1:0.01 to 1:0.8, said composition being such that, when dissolved in drinkable water for dilution, imparts a pH value ranging from 9 to 9.5 to the obtained solution, which do not cause sensory irritation to the oral cavity especially to the back of the mouth and throat, when swallowed.
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