Compositions Containing Purine and Pyrimidine Nucleosides, Peptides, and Manganese and Their Uses
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United States of America Patent
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Issued Date -
Oct 23, 2014
app pub date -
Nov 1, 2012
filing date -
Nov 1, 2011
priority date (Note) -
Abandoned
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Abstract
The invention provides methods of producing vaccines directed against methicillin-resistant Staphylococcus aureus (MRSA) or Venezuelan equine encephalitis virus (VEEV), with the methods comprising culturing, harvesting and/or suspending the MRSA or VEEV in the presence of a radiation-protective composition and irradiating the MRSA with a dose of radiation sufficient to render the MRSA or VEEV replication-deficient and/or non-infective. The radiation-protective compositions used in the methods of the present invention comprise at least one nucleoside, at least one antioxidant and at least one small peptide.
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