Tissue and blood-based miRNA biomarkers for the diagnosis, prognosis and metastasis-predictive potential in colorectal cancer

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United States of America Patent

PATENT NO 9868992
SERIAL NO

14215959

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Abstract

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Methods and compositions for the diagnosis, prognosis and classification of cancer, especially colorectal cancer, are provided. For example, in certain aspects methods for cancer prognosis using expression or methylation analysis of selected biomarkers are described. Particular aspects of the present invention may include methods and biomarkers for diagnosing or detecting colorectal cancer or metastasis in a subject by measuring a level of expression of biomarker miRNA such as miR-885-5p in the sample from the subject and evaluating the risk of developing cancer or metastasis in the subject.

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Patent Owner(s)

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BAYLOR RESEARCH INSTITUTE3434 LIVE OAK STREET DALLAS TX 75204

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Boland, C Richard Dallas, US 15 106
Goel, Ajay Dallas, US 21 89
Hur, Keun Dallas, US 4 9
Toiyama, Yuji Dallas, US 9 9

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