BIOCATALYSIS CELLS AND METHODS
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United States of America Patent
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Issued Date -
Nov 6, 2014
app pub date -
Oct 9, 2012
filing date -
Oct 10, 2011
priority date (Note) -
Abandoned
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Abstract
In one aspect, the invention provides a recombinant microbial cell modified to exhibit increased biosynthesis of a biosynthetic product compared to a wild-type control. In some cases, the biosynthetic product can be isocaproate; in other cases the biosynthetic product can be isovalerate. In another aspect, the invention provides methods of constructing such recombinant cells. In yet another aspect, the invention provides methods of using the cells to produce the biosynthetic product. In yet another aspect, the invention provides methods of harvesting organic acids from a fermentation culture.
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