Formulation for anti-α4β7 antibody

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United States of America Patent

PATENT NO 10040855
APP PUB NO 20140341885A1
SERIAL NO

14114835

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Abstract

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Antibody formulations are described comprising a mixture of an anti-α4β7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.

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Patent Owner(s)

  • MILLENNIUM PHARMACEUTICALS, INC.

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Jason Burlington, US 70 922
Diluzio, Willow Westford, US 14 750
Nguyen, Phoung M Cambridge, US 4 6
Palaniappan, Vaithianathan Andover, US 28 46
Varga, Csanad M Newton, US 28 47

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